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XPA antibody

KO/KD
Anti-XPA antibody used in Western Blot (WB). GTX55843
Anti-XPA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55843
Anti-XPA antibody used in Western Blot (WB). GTX55843
Anti-XPA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55843

Cat. No. GTX55843

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all XPA products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-273 of human XPA (NP_000371.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

XPA, DNA damage recognition and repair factor , XP1 , XPAC

Cellular Localization

Nucleus

Background

This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-XPA antibody used in Western Blot (WB). GTX55843

GTX55843 WB Image

KO/KD

WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX55843 XPA antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-XPA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55843

GTX55843 ICC/IF Image

ICC/IF analysis of A549 cells using GTX55843 XPA antibody.

Anti-XPA antibody used in Western Blot (WB). GTX55843

GTX55843 WB Image

WB analysis of various sample lysates using GTX55843 XPA antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-XPA antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55843

GTX55843 ICC/IF Image

ICC/IF analysis of GFP-RNF168 transgenic U2OS cells using GTX55843 XPA antibody.
Green : GFP-RNF168 fusion protein expression for DNA damage marker
Blue : DAPI

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399