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XRCC1 antibody

Anti-XRCC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX66634
Anti-XRCC1 antibody used in Western Blot (WB). GTX66634
Anti-XRCC1 antibody used in Western Blot (WB). GTX66634

Cat. No. GTX66634

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all XRCC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

69 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 520-570 of Human XRCC1.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

X-ray repair cross complementing 1 , RCC , SCAR26

Cellular Localization

Nucleus

Background

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-XRCC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX66634

GTX66634 IHC-P Image

IHC-P analysis of human lung carcinoma tissue using GTX66634 XRCC1 antibody.
Dilution : 1:100

Anti-XRCC1 antibody used in Western Blot (WB). GTX66634

GTX66634 WB Image

WB analysis of various samples using GTX66634 XRCC1 antibody.
Lane1 : HepG2 whole cell lysate
Lane2 : Raw264.7 whole cell lysate
Lane3 : H9C2 whole cell lysate
Dilution : 1:500

Anti-XRCC1 antibody used in Western Blot (WB). GTX66634

GTX66634 WB Image

WB analysis of various samples using GTX66634 XRCC1 antibody.
Lane1 : SK-OVCAR3 whole cell lysate(40ug)
Lane2 : Hela whole cell lysate(40ug)
Lane3 : HEK293T whole cell lysate(40ug)
Lane4 : PC12 whole cell lysate(40ug)
Lane5 : BV2 whole cell lysate(40ug)
Dilution : 1:500

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399