APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
2.5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
ZIP5 antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIP5.The immunogen is located within amino acids 330 - 380 of ZIP5.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
solute carrier family 39 member 5 , LZT-Hs7 , MYP24 , ZIP5
Background
The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.
Database
Research Area
DATA IMAGES
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GTX85132 IHC-P Image
IHC-P analysis of human spleen tissue using GTX85132 ZIP5 antibody. Working concentration : 20 μg/ml
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GTX85132 WB Image
WB analysis of human spleen tissue lysate using GTX85132 ZIP5 antibody. Working concentration : 1 μg/ml
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GTX85132 IHC-P Image
IHC-P analysis of human spleen tissue using GTX85132 ZIP5 antibody. Working concentration : 2.5 μg/ml
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REFERENCE
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REVIEW
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