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alpha 2 Macroglobulin antibody [F1-P1C11 #3]

Anti-alpha 2 Macroglobulin antibody [F1-P1C11 #3] used in ELISA (ELISA). GTX15643
Anti-alpha 2 Macroglobulin antibody [F1-P1C11 #3] used in Western Blot (WB). GTX15643
Anti-alpha 2 Macroglobulin antibody [F1-P1C11 #3] used in Western Blot (WB). GTX15643

Cat. No. GTX15643

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 F1-P1C11 #3

Isotype

 IgG1

Application

 WB, IP, ELISA, RIA

Reactivity

 Human
Package
100 μg ($399)
See all alpha 2 Macroglobulin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1-2 μg/ml
IP Assay dependent
ELISA 2 μg/ml
RIA Assay dependent
Not tested in other applications.

Calculated MW

163 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human plasma AMG

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

alpha-2-macroglobulin , A2MD , CPAMD5 , FWP007 , S863-7

Cellular Localization

Secreted

Background

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]

Database

  • Gene ID: 2 A2M
  • UniProt: P01023 A2M

Research Area

DATA IMAGES

Anti-alpha 2 Macroglobulin antibody [F1-P1C11 #3] used in ELISA (ELISA). GTX15643

GTX15643 ELISA Image

ELISA analysis of Alpha2-Macroglobulin recombinant protein diluted in carbonate/bicarbonate buffer (1 μg/ml, 100μl/well) using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3] at 0.03125 - 2 μg/mL (serial diluted).

Anti-alpha 2 Macroglobulin antibody [F1-P1C11 #3] used in Western Blot (WB). GTX15643

GTX15643 WB Image

WB analysis of 1000ng, 500ng, 250ng and 125ng of a human alpha 2 Macroglobulin recombinant protein using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3].
Dilution : 2 μg/ml

Anti-alpha 2 Macroglobulin antibody [F1-P1C11 #3] used in Western Blot (WB). GTX15643

GTX15643 WB Image

WB analysis of 5ul of human plasma using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3].
Dilution : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399