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cIAP2 antibody [C1C3]

Anti-cIAP2 antibody [C1C3] used in Western Blot (WB). GTX113128
Anti-cIAP2 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX113128
Anti-cIAP2 antibody [C1C3] used in Western Blot (WB). GTX113128
Anti-cIAP2 antibody [C1C3] used in Western Blot (WB). GTX113128

Cat. No. GTX113128

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399),
25 μl ($169)
See all cIAP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

Positive Control

rat spleen , HeLa , U87-MG , SK-N-SH , IMR32 , SK-N-AS

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 20% Glycerol

Preservative

0.025% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.67 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human cIAP2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2036572

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

baculoviral IAP repeat containing 3 , AIP1 , API2 , CIAP2 , HAIP1 , HIAP1 , IAP-1 , MALT2 , MIHC , RNF49 , c-IAP2

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-cIAP2 antibody [C1C3] used in Western Blot (WB). GTX113128

GTX113128 WB Image

cIAP2 antibody detects cIAP2 protein by western blot analysis.
A. 50 μg rat spleen lysate/extract
7.5% SDS-PAGE
cIAP2 antibody (GTX113128) dilution: 1:500
The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-cIAP2 antibody [C1C3] used in IHC (Paraffin sections) (IHC-P). GTX113128

GTX113128 IHC-P Image

Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using cIAP2(GTX113128) antibody at 1:100 dilution.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Anti-cIAP2 antibody [C1C3] used in Western Blot (WB). GTX113128

GTX113128 WB Image

cIAP2 antibody detects cIAP2 protein by western blot analysis. HeLa whole cell extract, HeLa cytosol and HeLa nuclear extract (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with cIAP2 antibody (GTX113128) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-cIAP2 antibody [C1C3] used in Western Blot (WB). GTX113128

GTX113128 WB Image

Various whole cell extracts (30 μg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with cIAP2 antibody [C1C3] (GTX113128) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

REFERENCE

Application Reference

Leu JS et al. Am J Respir Crit Care Med 2016; SP110b Controls Host Immunity and Susceptibility to Tuberculosis.
Application : WB
Reactivity : Human
Huang YT et al. Int J Mol Med 2016; 37 (1) : 83-91 Resveratrol alleviates the cytotoxicity induced by the radiocontrast agent, ioxitalamate, by reducing the production of reactive oxygen species in HK-2 human renal proximal tubule epithelial cells in-vitro.
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SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399
$ 169