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delta Sarcoglycan antibody

KO/KD
Anti-delta Sarcoglycan antibody used in Western Blot (WB). GTX32871
Anti-delta Sarcoglycan antibody used in IHC (Paraffin sections) (IHC-P). GTX32871
Anti-delta Sarcoglycan antibody used in IHC (Paraffin sections) (IHC-P). GTX32871
Anti-delta Sarcoglycan antibody used in Western Blot (WB). GTX32871

Cat. No. GTX32871

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all delta Sarcoglycan products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

32 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 61-290 of human SGCD (NP_000328.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887684

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sarcoglycan delta , 35DAG , CMD1L , DAGD , LGMDR6 , SG-delta , SGCDP , SGD

Cellular Localization

Cytoplasm, cytoskeleton

Background

The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-delta Sarcoglycan antibody used in Western Blot (WB). GTX32871

GTX32871 WB Image

WB analysis of various sample lysates using GTX32871 delta Sarcoglycan antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-delta Sarcoglycan antibody used in IHC (Paraffin sections) (IHC-P). GTX32871

GTX32871 IHC-P Image

IHC-P analysis of rat heart tissue using GTX32871 delta Sarcoglycan antibody.
Dilution : 1:100

Anti-delta Sarcoglycan antibody used in IHC (Paraffin sections) (IHC-P). GTX32871

GTX32871 IHC-P Image

KO/KD

The data was published in the journal Int J Mol Sci in 2019.PMID: 31689918

Anti-delta Sarcoglycan antibody used in Western Blot (WB). GTX32871

GTX32871 WB Image

KO/KD

The data was published in the journal Int J Mol Sci in 2019.PMID: 31689918

REFERENCE

Application Reference

Perez-Ortiz AC et al. Int J Mol Sci 2019; 20 (21) Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration.
Application : IHC-P
Reactivity : Mouse
Estrada-Mena FJ et al. Neurosci Lett 2017; 658 : 142-149 Effects of (-)-epicatechin on frontal cortex DAPC and dysbindin of the mdx mice.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399