APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 2 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rabbit, Chimpanzee, Gibbon, Gorilla, Marmoset(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human GRM1 / MGLUR1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
, GPRC1A , GRM1 , MGLU1 , MGLUR1 , PPP1R85 , SCAR13 , glutamate metabotropic receptor 1 , mGluR1 , Metabotropic Glutamate Receptor 1
Cellular Localization
Cell membrane
Background
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Database
Research Area
DATA IMAGES
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GTX13037 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX13037 mGluR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13037 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX13037 mGluR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13037 IHC-P Image
IHC-P analysis of human brain, neurons and glia tissue using GTX13037 mGluR1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13037 IHC-P Image
IHC-P analysis of spinal cord neurons tissue using GTX13037 mGluR1 antibody.
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GTX13037 IHC-P Image
IHC-P analysis of brain, thalamus, neurons tissue using GTX13037 mGluR1 antibody.
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REFERENCE
There are currently no references for mGluR1 antibody (GTX13037). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for mGluR1 antibody (GTX13037). Be the first to share your experience with this product.
