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p22phox antibody [44.1]

Cat. No. GTX80355

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 44.1

Isotype

 IgG2

Application

 WB

Reactivity

 Human
Package
50 μl ($399)
See all p22phox products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at 1:1000
Optimal dilutions should be determined experimentally by the researcher.

Calculated MW

21 kDa. ( Note )

Product Note

Human p22phox 29-TAGRF-33 & 183-PQVNPI-188

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Partially Purified human neutrophil flavocytochrome b (heparin Ultrogel/lectin affinity purification – in Triton X-100)

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cytochrome b-245 alpha chain , p22-PHOX

Cellular Localization

Cell membrane

Background

Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399