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MRP2 antibody, Internal

Anti-MRP2 antibody, Internal used in Western Blot (WB). GTX44679
Anti-MRP2 antibody, Internal used in Western Blot (WB). GTX44679

Cat. No. GTX44679

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Mouse
Package
50 μg ($419)
See all MRP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
Not tested in other applications.

Calculated MW

174 kDa. ( Note )

Positive Control

mouse spleen , mouse thymus

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

A synthetic peptide corresponding to an Internal region of Mouse MRP2

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

ATP-binding cassette, sub-family C (CFTR/MRP), member 2 , AI173996 , Abc30 , Cmoat , Mrp2 , cMRP

Cellular Localization

Apical cell membrane

Background

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the canalicular surface of the hepatocyte and in biliary transport, and appears to contribute to drug resistance in mammalian cells. Several different mutations in the human gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Alternative splice variants have been observed for this gene; however, they have not been fully described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MRP2 antibody, Internal used in Western Blot (WB). GTX44679

GTX44679 WB Image

WB analysis of mouse thymus tissue using GTX44679 MRP2 antibody at 1.0μg/ml.

Anti-MRP2 antibody, Internal used in Western Blot (WB). GTX44679

GTX44679 WB Image

WB analysis of mouse spleen tissue using GTX44679 MRP2 antibody at 0.2-1μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419