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CX3CR1 antibody

KO/KD Orthogonal
Anti-CX3CR1 antibody used in Flow cytometry (FACS). GTX27200
Anti-CX3CR1 antibody used in Western Blot (WB). GTX27200

Cat. No. GTX27200

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, IHC-Fr, FACS, IP, Neutralizing/Inhibition

Reactivity

 Human, Rat
Package
50 μg ($399)
See all CX3CR1 products

APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100 - 1/500. IHC-Fr: Use at a dilution of 1/100 - 1/500. IP: Use at a dilution of 1/300 - 1/800. Neut: Use at an assay dependent dilution. WB: Use at a dilution of 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

40 kDa. ( Note )

Product Note

Recombinant and natural rat CX3CR1

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Recombinant amino terminal fragment (Rat).

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_386034

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-X3-C motif chemokine receptor 1 , Rbs11

Cellular Localization

Cell membrane

Background

member of the rhodopsin family of G-protein coupled receptors; may act as a receptor for a chemokine peptide ligand [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-CX3CR1 antibody used in Flow cytometry (FACS). GTX27200

GTX27200 FACS Image

Anti-CX3CR1 antibody used in Western Blot (WB). GTX27200

GTX27200 WB Image

KO/KD Orthogonal

The data was published in the journal Nat Commun in 2018.PMID: 29367702

REFERENCE

Application Reference

Cankun Zheng et al. Front Pharmacol 2022; 13 : 848310 CX3CL1 Worsens Cardiorenal Dysfunction and Serves as a Therapeutic Target of Canagliflozin for Cardiorenal Syndrome.
Sidibe A et al. Nat Commun 2018; 9 (1) : 355 Angiogenic factor-driven inflammation promotes extravasation of human proangiogenic monocytes to tumours.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399