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DYNC1H1 antibody

Anti-DYNC1H1 antibody used in Western Blot (WB). GTX101452
Anti-DYNC1H1 antibody used in Western Blot (WB). GTX101452

Cat. No. GTX101452

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399),
25 μl ($169)
See all DYNC1H1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
ICC/IF Assay dependent
Not tested in other applications.

Calculated MW

532 kDa. ( Note )

Positive Control

SK-N-SH , SK-N-AS , NT2D1

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.89 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein corresponding to human DYNC1H1

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_10618610

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynein cytoplasmic 1 heavy chain 1 , CMT2O , DHC1 , DHC1a , DNCH1 , DNCL , DNECL , DYHC , Dnchc1 , HL-3 , SMALED1 , p22

Background

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-DYNC1H1 antibody used in Western Blot (WB). GTX101452

GTX101452 WB Image

DYNC1H1 antibody detects DYNC1H1 protein by western blot analysis. Whole cell extracts (30 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with DYNC1H1 antibody (GTX101452) at a dilution of 1:500.

Anti-DYNC1H1 antibody used in Western Blot (WB). GTX101452

GTX101452 WB Image

DYNC1H1 antibody detects DYNC1H1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 5 % SDS-PAGE, and blotted with DYNC1H1 antibody (GTX101452) diluted by 1:500

REFERENCE

Application Reference

Kristi McElmurry et al. J Cell Sci 2020; 133 (8) : jcs232983 Dynein-mediated microtubule translocation powering neurite outgrowth in chick and Aplysia neurons requires microtubule assembly.
Application : ICC/IF
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169