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UCP3 antibody

Anti-UCP3 antibody used in Western Blot (WB). GTX23477
Anti-UCP3 antibody used in Western Blot (WB). GTX23477

Cat. No. GTX23477

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat, Dog
Package
100 μg ($399)
See all UCP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5-2 μg/ml
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

uncoupling protein 3 (mitochondrial, proton carrier) , AI645527 , Slc25a9 , UCP-3

Cellular Localization

Mitochondrion inner membrane

Background

The uncoupling proteins (UCPs) are found in the inner mitochondrial membranes and belong to a family of mitochondrial anion transport proteins that include the phosphate and oxologutarate carriers and the ADP/ATP translocator. Three UCP subtypes have been identified and cloned. UCP-1 is abundantly expressed in brown adipose tissue of mammals. UCP-1 allows proton re-entry into the mitochondrial matrix without involving the F0-F1 ATPase which produces heat instead of ATP. It is thought that UCP-2 and 3 also dissipate the mitochondrial proton gradient produced by the respiratory chain in cells and tissues within which they are expressed. Studies have shown UCP-2 to be expressed by a variety of tissues. UCP-3 is expressed predominantly in brown adipose tissue, skeletal muscle, at lower levels in heart and smooth muscle, and is absent in liver and kidney.

Database

Research Area

DATA IMAGES

Anti-UCP3 antibody used in Western Blot (WB). GTX23477

GTX23477 WB Image

WB analysis of membrane enriched extracts (30 μg lysate) of L6 (Lane 1) and C2C12 (Lane 2) using GTX23477 UCP3 antibody.
Dilution : 1 μg/ml

Anti-UCP3 antibody used in Western Blot (WB). GTX23477

GTX23477 WB Image

WB analysis of recombinant human UCP-3 using GTX23477 UCP3 antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399