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FOG2 antibody

Anti-FOG2 antibody used in Western Blot (WB). GTX110166
Anti-FOG2 antibody used in Western Blot (WB). GTX110166
Anti-FOG2 antibody used in Western Blot (WB). GTX110166

Cat. No. GTX110166

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399),
25 μl ($169)
See all FOG2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

128 kDa. ( Note )

Positive Control

Mouse brain , rat brain , HeLa

Predict Reactivity

Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.96 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human FOG2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1952651

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

zinc finger protein, FOG family member 2 , DIH3 , FOG2 , SRXY9 , ZC2HC11B , ZNF89B , hFOG-2

Cellular Localization

Nucleus

Background

The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-FOG2 antibody used in Western Blot (WB). GTX110166

GTX110166 WB Image

FOG2/ZFPM2 antibody detects ZFPM2 protein by Western blot analysis.
A. 50 μg rat brain lysate/extract
5 % SDS-PAGE
FOG2/ZFPM2 antibody (GTX110166) dilution: 1:1000

Anti-FOG2 antibody used in Western Blot (WB). GTX110166

GTX110166 WB Image

Sample (50 ug of whole cell lysate)
A: Mouse brain
5% SDS PAGE
GTX110166 diluted at 1:3000

Anti-FOG2 antibody used in Western Blot (WB). GTX110166

GTX110166 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
7.5% SDS PAGE
GTX110166 diluted at 1:1000

REFERENCE

Application Reference

Zhang Z et al. Mech Dev 2018; (Epub) CRISPR/CAS9 ablation of individual miRNAs from a miRNA family reveals their individual efficacies for regulating cardiac differentiation.
Application : WB
Reactivity : Mouse
Mei S et al. PLoS One 2015; 10 (8) : e0135867 MicroRNA-200c Promotes Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating PTEN and FOG2 Expression.
Application : WB
Reactivity : Mouse
Kumarasamy S et al. Nat Commun 2015; 6 : 6252 Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension.
Application : WB
Reactivity : Rat
Xiang R et al. Braz J Med Biol Res 2012; 45 (2) : 131-8 The miR-17-92 cluster regulates FOG-2 expression and inhibits proliferation of mouse embryonic cardiomyocytes.
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 399
$ 169