APPLICATION
Product Note
The peptide was used in the production of GTX88922.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
C-ERDPDKQTQNKE
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Set Domain Containing 2 , Hbp231 , Hif-1 , Hip-1 , Hspc069 , Hypb , Kmt3A , Lls , Set2 , P231Hbp , Setd2
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Research Area
REFERENCE
There are currently no references for HYPB/SETD2 (internal region) blocking peptide (GTX88922-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for HYPB/SETD2 (internal region) blocking peptide (GTX88922-PEP). Be the first to share your experience with this product.