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United States (US)

MUC2 antibody

Cat. No. GTX72840

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC

Reactivity

 Human
Package
500 μl ($399)
See all MUC2 products

APPLICATION

Application Note

IHC, ICC (frozen or formalin–fixed paraffin-embedded (FFPE) tissue sections, cell smears) 1:50-1:200 using streptavidin-Biotin system or polymer system. Prediluted antibody is used directly without dilution. For FFPE tissue sections high temperature antigen retriever (boiling tissue in 10 mM citrate buffer for 10 minutes) enhances the signal and may require further dilution of antibody.

Calculated MW

540 kDa. ( Note )

Positive Control

Human colon carcinoma, LS 174 T colon cancer cell line

PROPERTIES

Form

Liquid

Buffer

10mM PO₄, 200mM NaCl 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic MUC2 (23 aa) tandem repeat consensus sequence

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_373911

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mucin 2, oligomeric mucus/gel-forming , MLP , MUC-2 , SMUC

Cellular Localization

Secreted

Background

This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Downregulation of this gene has been observed in patients with Crohn disease and ulcerative colitis. [provided by RefSeq, Oct 2016]

Database

Research Area

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399