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United States (US)

STAT2 peptide

Cat. No. GTX27999

Application

 IP

Species

 Human
Package
100 μg ($179)
See all STAT2 products

APPLICATION

Application Note

Blocking peptide for rabbit polyconal antibody to STAT2(GTX27965).

Calculated MW

98 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, BSA

Preservative

0.1% Sodium azide

Storage

Keep as concentrated solution, aliquot and store at 4ºC.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Peptide mapping to the carboxy terminus of human Stat2 p113.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal transducer and activator of transcription 2 , IMD44 , ISGF-3 , P113 , STAT113

Cellular Localization

Cytoplasm , Nucleus

Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Database

Research Area

REFERENCE

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Package List Price ($)
$ 179