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CD276 antibody [6A1]

Anti-CD276 antibody [6A1] used in IHC (Paraffin sections) (IHC-P). GTX82773
Anti-CD276 antibody [6A1] used in Western Blot (WB). GTX82773
Anti-CD276 antibody [6A1] used in Flow cytometry (FACS). GTX82773

Cat. No. GTX82773

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 6A1

Isotype

 IgG1

Application

 WB, IHC-P, FACS, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all CD276 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

57 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human CD276 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CD276 molecule , 4Ig-B7-H3 , B7-H3 , B7H3 , B7RP-2

Cellular Localization

Membrane

Background

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Database

Research Area

DATA IMAGES

Anti-CD276 antibody [6A1] used in IHC (Paraffin sections) (IHC-P). GTX82773

GTX82773 IHC-P Image

IHC-P analysis of cervical cancer tissue (left) and ovarian cancer tissue (right) using GTX82773 CD276 antibody [6A1].

Anti-CD276 antibody [6A1] used in Western Blot (WB). GTX82773

GTX82773 WB Image

WB analysis of HEK293 (1) and CD276(AA: 30-130)-hIgGFc transfected HEK293 (2) cell lysate using GTX82773 CD276 antibody [6A1].

Anti-CD276 antibody [6A1] used in Flow cytometry (FACS). GTX82773

GTX82773 FACS Image

FACS analysis of PC-3 cells using GTX82773 CD276 antibody [6A1].
Green : CD276
Purple : negative control

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399