APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 14 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Zebrafish, Gibbon, Gorilla, Opossum, Panda, Pufferfish, Xenopus, Platypus, Stickleback(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human BAI1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_425111
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
adhesion G protein-coupled receptor B1 , ADGRB1 , BAI1 , GDAIF , adhesion G proteincoupled receptor B1
Cellular Localization
Cell membrane,Cell projection,Phagocytic cup,Cell junction,Focal adhesion,Dendritic spine,Synapse,Postsynaptic cell membrane,Postsynaptic density,Secreted
Background
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX78163 IHC-P Image
IHC-P analysis of human brain, neurons tissue using GTX78163 BAI1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX78163 IHC-P Image
IHC-P analysis of human lung, adenocarcinoma tissue using GTX78163 BAI1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX78163 IHC-P Image
IHC-P analysis of human prostate, benign prostatic hyperplasia tissue using GTX78163 BAI1 antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
There are currently no references for BAI1 antibody (GTX78163). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for BAI1 antibody (GTX78163). Be the first to share your experience with this product.
