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SIPA1L2 antibody

Anti-SIPA1L2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85227
Anti-SIPA1L2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85227
Anti-SIPA1L2 antibody used in Western Blot (WB). GTX85227

Cat. No. GTX85227

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SIPA1L2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

190 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Rat Brain Tissue Lysate(GTX27942)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SIPA1L2 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1L2.The immunogen is located within the first 50 amino acids of SIPA1L2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

signal induced proliferation associated 1 like 2 , SPAL2

Background

Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.

Database

Research Area

DATA IMAGES

Anti-SIPA1L2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85227

GTX85227 IHC-P Image

IHC-P analysis of human brain tissue using GTX85227 SIPA1L2 antibody.
Working concentration : 5 μg/ml

Anti-SIPA1L2 antibody used in IHC (Paraffin sections) (IHC-P). GTX85227

GTX85227 IHC-P Image

IHC-P analysis of human brain tissue using GTX85227 SIPA1L2 antibody.
Working concentration : 20 μg/ml

Anti-SIPA1L2 antibody used in Western Blot (WB). GTX85227

GTX85227 WB Image

WB analysis of rat brain tissue lysate in (A) the absence and (B) the presence of blocking peptide using GTX85227 SIPA1L2 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399