GeneTex
United States (US)

CD8 alpha antibody [53-6.72] (FITC)

Cat No. GTX16189

Host Rat
Clonality Monoclonal
Clone Name 53-6.72
Isotype IgG2a
Application ICC/IF, IHC-Fr, FACS
Reactivity Mouse
APPLICATION

Application Note

FACS: Use at an assay dependent dilution. IF: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

26 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS, 1mg/ml BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human PBMCs stimulated with PHA.

Purification

Protein G purified

Conjugation

Fluorescein isothiocyanate (FITC)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cd8A Molecule,Cd8,Leu2,P32,Cd8A

Cellular Localization

Type I membrane protein.

Background

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

Database

Research Area

Package List Price ($)
$ 289