Western blot 1:500 - 50 kD band. Not yet tested in other applications.
THP-1 cell lysate
This antibody recognizes human, mouse and rat CX3CR1 (50 kD).
PBS with 0.02% sodium azide, pH 7.4
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.5mg/ml(Please refer to the vial label for the specific concentration.)
Synthetic peptide, corresponding to amino acids 175-189 of Human CX3CR 1.
Purified by immunoaffinity chroma-tography.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
CMKDR1, 1524, GPR13, P49238, V28, 601470, GPRV28, CMKBRL1, CX3CR1, CCRL1, Fractalkine
CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines (2).