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CaBP7 antibody

Anti-CaBP7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85169
Anti-CaBP7 antibody used in Western Blot (WB). GTX85169
Anti-CaBP7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85169

Cat. No. GTX85169

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all CABP7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
ICC/IF 4 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

Positive Control

HeLa Cell Slide(GTX25529) , HeLa Cell Lysate

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CaBP7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CaBP7.The immunogen is located within the first 50 amino acids of CaBP7.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

calcium binding protein 7 , CALN2

Cellular Localization

Cell membrane

Background

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Database

DATA IMAGES

Anti-CaBP7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85169

GTX85169 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX85169 CaBP7 antibody.
Working concentration : 4 μg/ml

Anti-CaBP7 antibody used in Western Blot (WB). GTX85169

GTX85169 WB Image

WB analysis of HeLa cell lysate using GTX85169 CaBP7 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-CaBP7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85169

GTX85169 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX85169 CaBP7 antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399