*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
This antibody reacts with free cardiac troponin I (cTnI) and cTnI forming complexes with other troponin components (in the presence of 5 mM EDTA). Not affected by heparin, phosphorylation, oxidation and troponin complex formation. Recognizes dephospho- and phospho- forms of cardiac Troponin I. Does not cross-react with skeletal muscle troponin I.
PBS pH 7.4, 0.09 % sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4º C.
Batch dependent(Please refer to the vial label for the specific concentration.)
Free human cardiac troponin I, native human cardiac troponin complex, or human cardiac troponin I peptides.
Protein A purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Troponin I3, Cardiac Type,Cmd1Ff,Cmd2A,Cmh7,Rcm1,Tnnc1,Ctni,Tnni3
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
GTX10225 WB Image
Recognition of the dephospho- and phospho- forms of human cardiac troponin I. A. Cardiac Troponin I antibody [10B11] (GTX10225); B. Cardiac Troponin I antibody [8E10] (GTX10232)