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DAO antibody

Anti-DAO antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53998
Anti-DAO antibody used in Western Blot (WB). GTX53998

Cat. No. GTX53998

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Mouse, Rat
Package
100 μl ($399)
See all DAO products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human DAO (NP_001908.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

D-amino acid oxidase , DAAO , DAMOX , OXDA

Background

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DAO antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX53998

GTX53998 ICC/IF Image

ICC/IF analysis of L929 cells using GTX53998 DAO antibody.
Blue : DAPI
Dilution : 1:100

Anti-DAO antibody used in Western Blot (WB). GTX53998

GTX53998 WB Image

WB analysis of rat kidney tissue lysate using GTX53998 DAO antibody.
Dilution : 1:3000
Loading : 25μg per lane

REFERENCE

Application Reference

Erika Ueda et al. Cells 2022; 11 (7) D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation.
Ohta T et al. Exp Neurol 2021; 343 : 113791 Therapeutic potential of d-cysteine against in vitro and in vivo models of spinocerebellar ataxia.
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399