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EMR2 antibody

Anti-EMR2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71219

Cat. No. GTX71219

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P, ELISA

Reactivity

 Human
Package
25 μg ($299)
See all EMR2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF Assay dependent
IHC-P 7.5 - 15 μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

Predict Reactivity

Gorilla(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from N-terminal extracellular domain of human EMR2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_375615

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

adhesion G protein-coupled receptor E2 , ADGRE2 , CD312 , EMR2 , VBU , adhesion G proteincoupled receptor E2

Cellular Localization

Cell membrane,Cell projection,Ruffle membrane

Background

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

Database

Research Area

DATA IMAGES

Anti-EMR2 antibody used in IHC (Paraffin sections) (IHC-P). GTX71219

GTX71219 IHC-P Image

IHC-P analysis of human spleen tissue using GTX71219 EMR2 antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299