Western blot (0.5-4 μg/ml), immunoprecipitation (2-10 μg/ml) and Immunohistochemistry (2-10 μg/ml). However, the optimal conditions should be determined individually. The antibody detects 12 kDa FKBP12 protein in samples from human, mouse, and rat origins.
This antibody is specific for FKBP12.
PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Fk506 Binding Protein 1A,Fkbp12,Fkbp,Fkbp1,Fkbp1A
FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.