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FKBP12 antibody

Anti-FKBP12 antibody used in Western Blot (WB). GTX59739

Cat No. GTX59739

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IP, IHC
Reactivity Human, Mouse, Rat
Package
100 μg ($329)
APPLICATION

Application Note

Western blot (0.5-4 μg/ml), immunoprecipitation (2-10 μg/ml) and Immunohistochemistry (2-10 μg/ml). However, the optimal conditions should be determined individually. The antibody detects 12 kDa FKBP12 protein in samples from human, mouse, and rat origins.

Calculated MW

12 kDa. ( Note )

Specificity/Sensitivity

This antibody is specific for FKBP12.
PROPERTIES

Form

Liquid

Buffer

PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Fk506 Binding Protein 1A,Fkbp12,Fkbp,Fkbp1,Fkbp1A

Background

FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.

Database

Research Area

DATA IMAGES
Anti-FKBP12 antibody used in Western Blot (WB). GTX59739

GTX59739 WB Image

Western blot analysis of FKBP12 expression in rat kidney tissue lysate.

REFERENCE
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Package List Price ($)
$ 329