APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| 4 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Bovine, Hamster, Elephant, Gibbon, Gorilla, Marmoset, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 18 amino acid peptide from 2nd extracellular domain of human GRPR.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
gastrin releasing peptide receptor , BB2 , BB2R , GRPR
Cellular Localization
Cell membrane
Background
Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX13339 IHC-P Image
IHC-P analysis of human pancreas, islet of langerhans tissue using GTX13339 GRPR antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13339 IHC-P Image
IHC-P analysis of brain cerebellum purkinje neurons tissue using GTX13339 GRPR antibody.
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GTX13339 IHC-P Image
IHC-P analysis of human lung, non-small cell carcinoma tissue using GTX13339 GRPR antibody.
Antigen retrieval : Heat-induced antigen retrieval
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GTX13339 IHC-P Image
IHC-P analysis of stomach tissue using GTX13339 GRPR antibody.
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GTX13339 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX13339 GRPR antibody.
Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
There are currently no references for GRPR antibody (GTX13339). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for GRPR antibody (GTX13339). Be the first to share your experience with this product.
