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Human Src protein, GST and His tag (active)

Human Src protein, GST and His tag (active). GTX01285-pro

Cat No. GTX01285-pro

Application

Functional Assay

Species

Human
Package
50 μg ($339),
20 μg ($259)

APPLICATION

Application Note

The specific activity was determined to be > 80 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.

Observed MW

81 kDa.

PROPERTIES

Form

Liquid

Buffer

50 mM Tris (pH 8.0), 100 mM NaCl, 20% glycerol, 0.3 mM DTT.

Storage

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Region/Sequence

N-terminal GST and poly His tagged; Met1-Leu536 of Human Src protein (P12931-1)

Expression System

Baculovirus (Insect cells)

Purity

> 90% by SDS-PAGE.

Endotoxin

< 1.0 EU/μg (determined by LAL method)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ASV,SRC1,THC6,c-SRC,p60-Src

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Human Src protein, GST and His tag (active). GTX01285-pro

GTX01285-pro Image

SDS-PAGE of 5 μg GTX01285-pro Human Src protein, GST and His tag (active).

REFERENCE

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