50 mM Tris (pH 8.0), 100 mM NaCl, 20% glycerol, 0.3 mM DTT.
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Batch dependent (Please refer to the vial label for the specific concentration.)
N-terminal GST and poly His tagged; Met1-Leu536 of Human Src protein (P12931-1)
Baculovirus (Insect cells)
> 90% by SDS-PAGE.
< 1.0 EU/μg (determined by LAL method)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]