GeneTex
United States (US)

IL1 beta recombinant protein

Cat No. GTX65130

Application ELISA, Functional Assay, Apuri, Blocking
Reactivity Human
Species Human
APPLICATION

Application Note

The ED50 as determined by the dose-dependent stimulation of thymidine uptake by murine C3H/HeJ thymocytes is <0.1 ng/ml, corresponding to a specific activity of >1x10^7 units/mg.

Calculated MW

17.0 kDa. ( Note )
PROPERTIES

Form

Lyophilized powder

Storage

We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or stored at –20ºC for future use.

Antigen Species

Human

Expression System

E. coli

Purification


Purity was assessed by SDS-PAGE (≥98%) and by HPLC (≥98%).

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Lymphocyteactivating factor (LAF), Leukocyte Endogenous Mediator (LEM), Catabolin, Endogenous Pyrogen (EP), Mononuclear Cell Factor (MCF), IL1B, Lymphocyte-activating factor (LAF)

Background

IL-1beta is a potent immuno-modulator that mediates a wide range of immune and inflammatory responses including the activation of B and T cells. Recombinant human IL-1beta is a 17.0 kDa protein containing 153 amino acid residues.

Research Area