APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.5-1 μg/ml |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes an epitope at the C-terminus of human, mouse, and rat NAK/TBK1 (NF-κB Activating Kinase and TANK-Binding Kinase 1). This antibody does not cross-react with IKKα, IKKβ, IKKε, or IKKγ.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide corresponding to aa 712-727 of human NAK/TBK1. This sequence is identical to that of mouse NAK/TBK1.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
FTDALS4 , NAK , T2K , TANK binding kinase 1 , TBK1
Cellular Localization
Cytoplasm
Background
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]
Database
Research Area
REFERENCE
There are currently no references for NAK / TBK1 antibody (GTX28121). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for NAK / TBK1 antibody (GTX28121). Be the first to share your experience with this product.