APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
1:50 |
Not tested in other applications.
Calculated MW
Product Note
Does not crossreact with PLCgamma2.
PROPERTIES
Form
Liquid
Buffer
10mM HEPES, 150mM NaCl, 0.01% BSA, 50% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide corresponding to the C-terminal residues of human Phospholipase C, gamma 1 (PLCg1).
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
NCKAP3 , PLC1 , PLC148 , PLCG1 , PLCII , PLCgamma1 , phospholipase C gamma 1 , PLC gamma 1 , PLC gamma I , PLC γ1
Cellular Localization
Cell projection,Lamellipodium,Ruffle
Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX30787 WB Image
WB analysis of untreated or PDGF-stimulated NIH3T3 cell lysate using GTX30787 PLCG1 antibody.
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GTX30787 IP Image
IP analysis of untreated or PDGF-stimulated NIH3T3 cell lysate using GTX30787 PLCG1 antibody.
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REFERENCE
There are currently no references for PLCG1 antibody (GTX30787). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for PLCG1 antibody (GTX30787). Be the first to share your experience with this product.