APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant full length Human PTPRO.
Purification
Purified by antigen-affinity chromatography
From serum
Purity
> 95% (by SDS-PAGE)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
protein tyrosine phosphatase receptor type O , GLEPP1 , NPHS6 , PTP-OC , PTP-U2 , PTPROT , PTPU2 , R-PTP-O
Cellular Localization
Membrane; Single-pass type I membrane protein
Background
This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011]
Database
Research Area
DATA IMAGES
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GTX66615 IHC-P Image
IHC-P analysis of human stomach carcinoma tissue using GTX66615 PTPRO antibody. Left : Primary antibody Right : Negative control Dilution : 1:50
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GTX66615 IHC-P Image
IHC-P analysis of human kidney carcinoma tissue using GTX66615 PTPRO antibody. Left : Primary antibody Right : Negative control Dilution : 1:50
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REFERENCE
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REVIEW
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