GeneTex
United States (US)

Retinoic Acid Receptor alpha antibody [763]

Cat No. GTX30167

Host Mouse
Clonality Monoclonal
Clone Name 763
Isotype IgG1
Application WB
Reactivity Human, Rat
APPLICATION

Application Note

For WB: Use at a dilution of 1:1,000. A ~48 kDa band can be seen in a Western blot analysis, using rat brain hippocampal homogenate. Tested in TBST (20 mM Tris/HCl (7.6), 137 mM NaCl, 1% Tween-20) containing 5% nonfat milk and 0.05% NaN3. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

51 kDa. ( Note )

Specificity/Sensitivity

This antibody is specific for Retinoic acid receptor, alpha isotype.
PROPERTIES

Form

Liquid

Buffer

10 mM Hepes, pH7.5, 150 mM NaCl, 100 ug/ml BSA and 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

NR1B1, 5914, RAR alpha, RARA, P10276, 180240, RAR

Background

Retinoids can reverse various premalignant lesions as well as prevent some second primary tumors. The effects of retinoids are regulated by retinoic acid receptors (RAR) and retinoid X receptors, which act as ligand-activated transcription factors. Ligand-dependent transcriptional activation of RARs is a multistep process that ends with the formation of a multimeric co-activator complex on regulated promoters (1,2).

Database

Research Area

Package List Price ($)
$ 319