*Optimal dilutions/concentrations should be determined by the researcher.
|0.5 - 1 μg/mL
Not tested in other applications.
THP-1 Cell Slide(GTX25540) , THP-1 Cell Lysate(GTX27913)
Recognizes SIRP alpha 1, 2 and 3.
PBS with 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
SIRP alpha antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human SIRP alpha 1.The immunogen is located within the last 50 amino acids of SIRP alpha.
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Signal Regulatory Protein Alpha,Bit,Cd172A,Mfr,Myd-1,P84,Ptpns1,Shps1,Sirp,Sirpa
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 20
GTX31256 ICC/IF Image
ICC/IF analysis of THP-1 cells using GTX31256 SIRP alpha antibody.
Working concentration : 1 μg/ml
GTX31256 WB Image
WB analysis of THP-1 cell lysate using GTX31256 SIRP alpha antibody.
Working concentration : 0.5 μg/ml