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SnoN antibody

Anti-SnoN antibody used in IHC (Paraffin sections) (IHC-P). GTX16977
Anti-SnoN antibody used in IHC (Paraffin sections) (IHC-P). GTX16977
Anti-SnoN antibody used in Western Blot (WB). GTX16977

Cat. No. GTX16977

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all SnoN products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 - 1 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

Positive Control

A431 Cell Lysate(GTX27909) , Mouse Lung Tissue Lysate(GTX27933)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

SnoN antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SnoN.The immunogen is located within the first 50 amino acids of SnoN.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

SKI like proto-oncogene , SNO , SnoA , SnoI , SnoN

Background

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Database

Research Area

DATA IMAGES

Anti-SnoN antibody used in IHC (Paraffin sections) (IHC-P). GTX16977

GTX16977 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX16977 SnoN antibody.
Working concentration : 5 μg/ml

Anti-SnoN antibody used in IHC (Paraffin sections) (IHC-P). GTX16977

GTX16977 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX16977 SnoN antibody.
Working concentration : 20 μg/ml

Anti-SnoN antibody used in Western Blot (WB). GTX16977

GTX16977 WB Image

WB analysis of A431 cell lysate using GTX16977 SnoN antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399