Summary
The RMT3-23 antibody reacts with mouse CD366 which is also known as Tim-3 (T cell immunoglobulin and mucin domain containing protein-3). Tim-3 is expressed on activated monocytes, macrophages, dendritic cells, and mast cells. Additionally, Tim-3 is found on Th1 lymphocytes and functions as an inhibitory receptor involved in the maintenance of immune homeostasis and self tolerance.
Form
Liquid
Buffer
10mM NaH₂PO₄, 150mM NaCl, 0.1% Gelatin
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Mouse
Immunogen
Tim-3-Ig, consisting of amino acids 1-191 of mouse Tim-3, coupled with the Fc portion of mouse IgG2a.
Purification
Purified by affinity chromatography
From tissue culture supernatant
Conjugation
Phycoerythrin (PE)
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.