Thrombin Receptor (Cleaved-Ser42) Antibody detects endogenous levels of fragment of activated Thrombin Receptor resulting from cleavage adjacent to Ser42.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
The immunogen corresponding to a region within amino acids 23 and 72 of human Thrombin Receptor.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Coagulation Factor Ii Thrombin Receptor,Cf2R,Htr,Par-1,Par1,Tr,F2R
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.