GeneTex
United States (US)

Thrombin Receptor (cleaved Ser42) antibody

PAR1-cleaved-Ser42-antibody-GTX86903-WB-1_18121411_917.jpg

Cat No. GTX86903

Host Rabbit
Clonality Polyclonal
Application WB, ELISA
Reactivity Human
APPLICATION

Application Note

We recommend the following starting dilutions:

WB: 1:500~1:1000
ELISA: 1:20000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

46 kDa. ( Note )

Specificity/Sensitivity

Thrombin Receptor (Cleaved-Ser42) Antibody detects endogenous levels of fragment of activated Thrombin Receptor resulting from cleavage adjacent to Ser42.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The immunogen corresponding to a region within amino acids 23 and 72 of human Thrombin Receptor.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Coagulation Factor Ii Thrombin Receptor,Cf2R,Htr,Par-1,Par1,Tr,F2R

Background

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Database

Research Area

DATA IMAGES
PAR1-cleaved-Ser42-antibody-GTX86903-WB-1_18121411_917.jpg

GTX86903 WB Image

Western blot analysis of extracts from Jurkat cells, using PAR1 (Cleaved-Ser42) Antibody. The lane on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339