GeneTex
United States (US)

Transferrin antibody

Cat No. GTX29538

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, IHC-Fr
Reactivity Human
APPLICATION

Application Note

This antibody may be diluted to a titer of 1:50-1:100 in an ABC method. We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation and dilutions should be determined by the user.

Calculated MW

77 kDa. ( Note )

Positive Control

Secreted

Specificity/Sensitivity

This antibody reacts with human transferrin. It stains hepatocytes in fetal liver, epithelial cells of colon adenocarcinoma and cells of normal liver.
PROPERTIES

Form

Liquid

Buffer

This antibody contains sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

Transferrin isolated from human serum.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

PRO1557, TF, PRO2086, 7018, P02787, Transferrin, 190000

Background

This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq]

Database

Research Area