APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
4 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Chimpanzee, Elephant, Gibbon, Gorilla, Marmoset, Orangutan, Panda(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM2.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_375599
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cholinergic receptor muscarinic 2 , CHRM2 , HM2 , mAChR M2 , Muscarinic Acetylcholine Receptor 2
Cellular Localization
Cell membrane,Cell junction,Synapse,Postsynaptic cell membrane
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX71169 IHC-P Image
IHC-P analysis of human skin, melanoma tissue using GTX71169 mAChR M2 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71169 IHC-P Image
IHC-P analysis of human brain, glioblastoma tissue using GTX71169 mAChR M2 antibody. Antigen retrieval : Heat-induced antigen retrieval
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GTX71169 IHC-P Image
IHC-P analysis of brain, hypothalamus tissue using GTX71169 mAChR M2 antibody.
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GTX71169 IHC-P Image
IHC-P analysis of brain, parkinson's disease neuron lewy bodybrain, parkinson's disease neuron lewy body tissue using GTX71169 mAChR M2 antibody.
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GTX71169 IHC-P Image
IHC-P analysis of human brain, neurons and glia tissue using GTX71169 mAChR M2 antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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