APPLICATION
Application Note
Measured by its ability to inhibit GM-CSF dependent proliferation of TF1 human erythroleukemic cells. The ED₅₀ for this effect is less or equal to 10 μg/ml in the presence of 0.5 ng/ml GM-CSF.
Observed MW
40-57 kDa.
PROPERTIES
Form
Liquid
Buffer
PBS, 10% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Region/Sequence
C-terminal His-Tag; Length: 310 a.a. Sequence: ADPLIPEKSD LRTVAPASSL NVRFDSRTMN LSWDCQENTT FSKCFLTDKK NRVVEPRLSN NECSCTFREI CLHEGVTFEV HVNTSQRGFQ
QKLLYPNSGR EGTAAQNFSC FIYNADLMNC TWARGPTAPR DVQYFLYIRN SKRRREIRCP YYIQDSGTHV GCHLDNLSGL TSRNYFLVNG
TSREIGIQFF DSLLDTKKIE RFNPPSNVTV RCNTTHCLVR WKQPRTYQKL SYLDFQYQLD VHRKNTQPGT ENLLINVSGD LENRYNFPSS
EPRAKHSVKI RAADVRILNW SSWSEAIEFG SDDGHHHHHH
Expression System
Baculovirus
Purity
> 90% by SDS-PAGE.
Endotoxin
< 1.0 EU/μg (determined by LAL method)
Conjugation
Unconjugated
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
colony stimulating factor 2 receptor alpha subunit , CD116 , CDw116 , CSF2R , CSF2RAX , CSF2RAY , CSF2RX , CSF2RY , GM-CSF-R-alpha , GMCSFR , GMR , SMDP4 , alphaGMR
Background
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX67018-pro Image
3 μg of GTX67018-pro Human GM-CSF Receptor alpha protein (active) by SDS-PAGE under reducing condition and visualized by coomassie blue stain
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REFERENCE
There are currently no references for Human GM-CSF Receptor alpha protein, His tag (active) (GTX67018-pro). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Human GM-CSF Receptor alpha protein, His tag (active) (GTX67018-pro). Be the first to share your experience with this product.