GeneTex

  • Country / Location Selection

United States (US)

Human BCDIN3D protein, His tag

Human BCDIN3D protein, His tag. GTX57354-pro

Cat. No. GTX57354-pro

Species

 Human
Package
50 μg ($289)
See all BCDIN3D protein products

APPLICATION

Observed MW

33 kDa.

PROPERTIES

Form

Liquid

Buffer

20mM Tris-HCl, 200mM NaCl, 40% Glycerol, 1mM DTT, 2mM EDTA

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.25 mg/ml (Please refer to the vial label for the specific concentration.)

Region/Sequence

Full length protein, N-terminal His-Tag; MGSSHHHHHH SSGLVPRGSH MGSMAVPTEL DGGSVKETAA EEESRVLAPG AAPFGNFPHY SRFHPPEQRL RLLPPELLRQ LFPESPENGP ILGLDVGCNS GDLSVALYKH FLSLPDGETC SDASREFRLL CCDIDPVLVK RAEKECPFPD ALTFITLDFM NQRTRKVLLS SFLSQFGRSV FDIGFCMSIT MWIHLNHGDH GLWEFLAHLS SLCHYLLVEP QPWKCYRAAA RRLRKLGLHD FDHFHSLAIR GDMPNQIVQI LTQDHGMELI CCFGNTSWDR SLLLFRAKQT IETHPIPESL IEKGKEKNRL SFQKQ

Expression System

E. coli

Purity

> 85% by SDS-PAGE.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BCDIN3 domain containing RNA methyltransferase

Cellular Localization

Cytoplasm

Background

This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]

Database

DATA IMAGES

Human BCDIN3D protein, His tag. GTX57354-pro

GTX57354-pro Image

3μg Human BCDIN3D protein (GTX57354-pro) by SDS-PAGE under reducing condition and visualized by coomassie blue stain.

REFERENCE

There are currently no references for Human BCDIN3D protein, His tag (GTX57354-pro). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Human BCDIN3D protein, His tag (GTX57354-pro). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Package List Price ($)
$ 289