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Interleukin-6 (IL-6) is a cytokine with a high clinical profile due to its involvement in inflammatory processes, autoimmune disease, and cancer progression. IL-6 can interact with both soluble and transmembrane forms of the IL-6 receptor α, with binding to the soluble receptor leading to pro-inflammatory signaling while anti-inflammatory signaling follows transmembrane receptor binding (1, 2). Specific targeting of IL-6-dependent pro-inflammatory events, a major focus of therapeutics development, will be greatly accelerated with better understanding of the underlying mechanistic features of IL-6 biology.
GeneTex has introduced a new recombinant rabbit monoclonal IL-6 antibody with high specificity and sensitivity to its catalog of conventional mouse monoclonal and rabbit polyclonal IL-6 reagents. Matched sandwich ELISA (sELISA) pairs (see below) using this rabbit monoclonal antibody in combination with different mouse monoclonal antibodies allow detection of human IL-6. In addition, GeneTex offers recombinant human IL-6 protein (GTX135982-pro & GTX135983-pro) in two useful formats. Please review the products below and go to www.genetex.com to learn more.
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